Percutaneous coronary intervention of chronically occluded vessels can result in significant improvement in
symptoms, relieve myocardial ischemia, and affect a reduction in major adverse cardiac events. Likelihood of achieving
successful revascularization can be significantly enhanced with a thorough understanding of the pathology of these occluded
coronary arteries. In this chapter, various steps and techniques to cross the CTO lesion and recanalize it are discussed
Keywords: Chronic total occlusion, pathology, percutaneous coronary intervention.
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