Proteomic Analysis of Genetic Improvement of Farmed Tilapia (GIFT) Liver

Author(s): J. J. Zhu, D. L. Huang, Q. Fu, Q. W. Ao, Y. Tan, G. Q. Lan, Y. F. Guo, M. Zhang, X. Gan, H.S. Jiang.

Journal Name: Current Proteomics

Volume 12 , Issue 2 , 2015

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Graphical Abstract:


The freshwater fish of the world can be divided into four categories: herbivores, omnivores, carnivores, and limnivores according to their diet. Tilapias are omnivorous, consuming detrital material, invertebrates, small fry, and vegetation ranging from macroalgae to rooted plants. Tilapia is also a popular fish for aquaculture. The liver of tilapia is one of the major organs of the digestive system, and plays an important role in synthesizing proteins related to food metabolism, energy storage, waste removal, and immune system support. We used 2-D HPLC-MS/MS and mascot software. These proteins were related to energy metabolism, ceJiang, HSll defense, stress, digestion immunity, and detoxification. Our results provide insight into the basic physiological function of the liver and potential mechanisms of liver diseases in GIFT tilapia.

Keywords: Proteome, GIFT tilapia, two dimensional electrophoresis, liver, physiology.

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Article Details

Year: 2015
Page: [137 - 142]
Pages: 6
DOI: 10.2174/157016461202150903115040
Price: $25

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