Xenobiotic and Non-Xenobiotic Interventions in the Microbiome Therapeutics

Author(s): Vipin Kumar, Pradeep Kumar, Vikas Sharma.

Journal Name: Current Drug Metabolism

Volume 16 , Issue 4 , 2015

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Abstract:

It is now very much clear that the microbiome plays an important part in human health. Microbiome is associated with several diseases and targeting the whole microbiome is certainly a challenge before the scientists. The “Human Microbiome Project” is continually exploring certain therapeutic targets inside microbiome landscape that could be utilized for the treatment of microbiome associated diseases. Additionally, associated research across the globe is going on and now some potential targets are available that might be beneficial for the designing and synthesis of novel drugs. In this review, we made an effort to discuss all the potential targets and corresponding possible drugs/treatments available for each of them. However, it is not possible to treat all microbiome associated diseases with a single drug/drug combination. Therefore, for different diseases, different treatments/drugs (whether xenobiotic or non-xenobiotic) could be used for better therapeutic efficacy.

Keywords: Bacteriocins, drug, microbiome, probiotics, traditional chinese medicines, vitamin D, xenobiotic.

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Article Details

VOLUME: 16
ISSUE: 4
Year: 2015
Page: [284 - 293]
Pages: 10
DOI: 10.2174/138920021604150902180008
Price: $58

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