Cyanide Detection using Azo-acylhydrazone in Aqueous Media with High Sensitivity and Selectivity

Title:Cyanide Detection using Azo-acylhydrazone in Aqueous Media with High Sensitivity and Selectivity

Volume: 12 Issue: 2

Author(s): Jing Qi, Jinghan Hu, You Sun and Jianbin Li

Affiliation:

Keywords: Colorimetric recognition, cyanide detect, anions sensor, test strip.

Abstract: The cyanide anion (CN⁻) is known to be an extremely toxic anion and can directly lead to the death of human beings in several minutes because it strongly binds cytochrome-c, thereby disrupting the mitochondrial electron-transport chain and causing a decreased oxidative metabolism and oxygen utilization. A colorimetric sensor L1 bearing azosalicylic aldehyde of benzoyl hydrazone was designed and synthesized. The binding property of the sensor L1 with anions such as F⁻, Cl⁻, Br⁻, I⁻, CH₃COO⁻, H₂PO₄⁻, HSO₄⁻, ClO₄⁻, CN⁻ and SCN⁻, was examined by UV-vis and 1H NMR spectra. The result showed that sensor L1 has behaved good selectivity and high sensitivity for CN⁻ in DMSO/H₂O (5:5, v/v) binary solutions. When CN⁻ was added to the solution containing L1, a dramatic color change from colorless to red was observed, while the other anions did not cause noticeable changes. And the detection limits were 1.0×10⁻⁵ mol•L^-1 and 3.7×10⁻⁸ mol•L^-1 of CN⁻ from visual color changes and UV-vis spectrum changes respectively. Furthermore, test strips based on sensor L1 were fabricated, and sensor L1 could be served as practical colorimetric sensor to detect CN⁻ for “in-the-field” measurement. In addition, test strips based on L1 were fabricated, which could serve as a practical colorimetric sensor to detect CN⁻ in field measurements or in test kits.

Cite this article as:

Qi Jing, Hu Jinghan, Sun You and Li Jianbin, Cyanide Detection using Azo-acylhydrazone in Aqueous Media with High Sensitivity and Selectivity, Current Analytical Chemistry 2016; 12 (2) . https://dx.doi.org/10.2174/1573411011666150827194259