The colonization and infection with methicillin-resistant Staphylococcus aureus
is a major health problem in hospitals and long-term care facilities. Although bacteriaemias
with MRSA (methicillin-resistant Staphylococcus aureus) can be treated with vancomycin and other reserve
antibiotics, 20% of patients cannot be successfully cured. Inpatients colonized with MRSA are isolated in
hospitals according to the guidelines of the Robert-Koch-Institute, although in long-term care facilities these
patients are not urgently isolated. Active decolonization measures are taken to eradicate colonization with
MRSA. In order to reduce MRSA colonization, it could be possible to administer cultures of Staphylococcus
epidermidis which have no antibiotic resistance, so that physiological genes could be conferred from
Staphylococcus epidermidis to MRSA bacteria.
Keywords: Bacteriaemia, colonization, daptomycin, extended spectrum ß-lactamase, methicillin-resistant
Staphylococcus aureus, multi-resistance, Staphyloccus epidermidis, vancomyin.
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