Title:Advances in the Enantioselective Metal-catalyzed N-H and O-H Insertion Reactions with Diazocarbonyl Compounds
VOLUME: 12 ISSUE: 5
Author(s):Antonio C. B. Burtoloso, João V. Santiago, Barbara Bernardim and Alexánder G. Talero
Affiliation:Instituto de Química de São Carlos, Universidade de São Paulo, CEP 13560-970, São Carlos, Brasil.
Keywords:Asymmetric catalysis, carbenes, diazocarbonyls, enantioselective, insertion reactions, metal catalysis.
Abstract:Insertion of diazocarbonyl-derived metallocarbenes into X-H bonds (X= H, C, Si, N, O, S, P, Se) has
proven to be a very important method for the construction of C-X bonds in organic chemistry. This mini-review
provides a brief historical background, mechanistic aspects and a summary of recent breakthroughs in the area of
enantioselective metal-catalyzed N-H and O-H insertion reactions.
