T-cell activation affects microRNA (miRNA) expression in T-cell subsets. However, little
is known about the kinetics of miRNA regulation and possible differences between CD4 and CD8 T
cells. In this study we set out to analyze the kinetics of activation-induced expression regulation of
twelve pre-selected miRNAs. The dynamics of the expression of these miRNAs was studied in sorted
CD4 and CD8 CD45RO- T cells of healthy individuals stimulated with
Keywords: Activation, antibodies, immune, microRNA, miRNA regulation, T cell.
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