Nucleosides with Modified Sugar Ring: Synthesis and Biological Activities

Author(s): Sarbjit Singh, Deepak Bhattarai, Gajulapati Veeraswamy, Yongseok Choi, Kyeong Lee.

Journal Name: Current Organic Chemistry

Volume 20 , Issue 8 , 2016

Become EABM
Become Reviewer

Graphical Abstract:


Abstract:

In the recent few years, the emergence of nucleosides containing modified sugar ring or modified base moiety has gained much attention due to their enhanced biological activities as compared to parent nucleosides containing 5-carbon ribose or deoxyribose sugar ring. In this review, we highlight the recent advances in synthesis and biological activities of nucleosides containing modified sugar rings reported between years 2010 to 2015.

Keywords: Functionalized nucleosides, modified nucleosides, fluorinated nucleosides, selenonucleosides, thionucleosides, biologically active nucleosides.

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 20
ISSUE: 8
Year: 2016
Page: [856 - 897]
Pages: 42
DOI: 10.2174/1385272819666150803235458
Price: $58

Article Metrics

PDF: 33
HTML: 1
EPUB: 1
PRC: 1

Special-new-year-discount