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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Nucleosides with Modified Sugar Ring: Synthesis and Biological Activities

Author(s): Sarbjit Singh, Deepak Bhattarai, Gajulapati Veeraswamy, Yongseok Choi and Kyeong Lee

Volume 20, Issue 8, 2016

Page: [856 - 897] Pages: 42

DOI: 10.2174/1385272819666150803235458

Price: $65

Abstract

In the recent few years, the emergence of nucleosides containing modified sugar ring or modified base moiety has gained much attention due to their enhanced biological activities as compared to parent nucleosides containing 5-carbon ribose or deoxyribose sugar ring. In this review, we highlight the recent advances in synthesis and biological activities of nucleosides containing modified sugar rings reported between years 2010 to 2015.

Keywords: Functionalized nucleosides, modified nucleosides, fluorinated nucleosides, selenonucleosides, thionucleosides, biologically active nucleosides.

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