Nano-constructed Carriers Loaded With Antioxidant: Boon For Cardiovascular System

Author(s): Ashay Jain, Prashant Kesharwani, Neeraj Kumar Garg, Atul Jain, Pradip Nirbhavane, Nitin Dwivedi, Sanjeev Banerjee, Arun K. Iyer, Mohd Cairul Iqbal Mohd Amin.

Journal Name: Current Pharmaceutical Design

Volume 21 , Issue 30 , 2015

Abstract:

In the last couple of decades antioxidant agents have entered the health market as an easy and attractive means of managing diseases. These agents are of enormous interest for an increasingly health-concerned society, and may be particularly relevant for prophylaxis of a number of diseases i.e. arthritis, cancer, metabolic and cardiovascular diseases, osteoporosis, cataracts, brain disorders, etc. Antioxidants are also favorable to vascular healthiness and symbolize useful compounds because they are able to diminish overall cardiovascular risk by acting analogous to first line therapy or as adjuvants in case of failure or in situations where first line therapy cannot be used. Furthermore, well-designed trials are indeed needed to improve the therapeutic efficacy and health benefits of antioxidants. Numerous in vivo proof-of-concepts studies are offered to underline the feasibility of nanostructure system in order to optimizing the delivery of cardiovascular drugs. The present review highlights the recent approaches for management of cardiovascular disease using different vesicular and particulate carriers, including liposomes, nanoparticles, and nanoemulsions, with a primary emphasis on those which are expected to enhance the antioxidants level.

Keywords: Antioxidants, cardiovascular diseases, liposomes, nanoparticles, nanoemulsions.

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Article Details

VOLUME: 21
ISSUE: 30
Year: 2015
Page: [4456 - 4464]
Pages: 9
DOI: 10.2174/1381612821666150803152033
Price: $58

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