Current Bioinformatics

Yi-Ping Phoebe Chen
Department of Computer Science and Information Technology
La Trobe University
Melbourne
Australia

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An Improved Mathematical Object for Graphical Representation of DNA Sequences

Author(s): Yan Peng, Yuewu Liu.

Abstract:

An improved mathematical object is presented for analyzing the similarity and dissimilarity of DNA sequences. The kernel of it is to employ the changes of the x-coordinates and y-coordinates of the points corresponding to the bases of DNA sequence in the method of graphical representation, respectively. Compared with the traditional methods based on the distances between points, a more detailed consideration on the measurement between points is made in this new method, so more information of DNA sequence is exploited. It can distinguish any form of symmetrical curves corresponding to DNA sequences, and this advantage can hardly be achieved by traditional methods. Furthermore, the contrast experiments show that this method increases the precision by about 50%.

Keywords: DNA sequence, graphical representation, mathematical object, sequence comparison, similarity/dissimilarity matrix, x, y-coordinates.

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Article Details

VOLUME: 10
ISSUE: 3
Year: 2015
Page: [332 - 336]
Pages: 5
DOI: 10.2174/157489361003150723135559
Price: $58