Title:Microwave Assisted Reactions of 5-Amino-1, 3-disubstituted Pyrazoles with Some Benzaldehydes
VOLUME: 3 ISSUE: 2
Author(s):Agnieszka Puchala, Magdalena Marcinkowska and Danuta Rasala
Affiliation:Institute of Chemistry, Jan Kochanowski University, Swietokrzyska 15G, 25-406 Kielce, Poland.
Keywords:Aldehydes, bis-pyrazolo[3, 4-b;4’, 3’-e]pyridines, diamine derivatives, N-heterocycles,
microwave assisted synthesis, pyrazoles.
Abstract:The microwave-promoted reactions of 5-amino-1,3-disubstituted pyrazoles with benzaldehyde,
4-chloro- and 4-nitrobenzaldehydes are presented. The use of microwave irradiation with variable
input power leads to different products, such as Schiff bases, diamine derivatives and bispyrazolo[
3,4-b;4’3’-e]pyridines in moderate to excellent yields and high purities.