Microwave Assisted Reactions of 5-Amino-1, 3-disubstituted Pyrazoles with Some Benzaldehydes

Author(s): Agnieszka Puchala, Magdalena Marcinkowska, Danuta Rasala.

Journal Name: Current Microwave Chemistry

Volume 3 , Issue 2 , 2016

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Abstract:

The microwave-promoted reactions of 5-amino-1,3-disubstituted pyrazoles with benzaldehyde, 4-chloro- and 4-nitrobenzaldehydes are presented. The use of microwave irradiation with variable input power leads to different products, such as Schiff bases, diamine derivatives and bispyrazolo[ 3,4-b;4’3’-e]pyridines in moderate to excellent yields and high purities.

Keywords: Aldehydes, bis-pyrazolo[3, 4-b;4’, 3’-e]pyridines, diamine derivatives, N-heterocycles, microwave assisted synthesis, pyrazoles.

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Article Details

VOLUME: 3
ISSUE: 2
Year: 2016
Page: [97 - 101]
Pages: 5
DOI: 10.2174/2213335602666150706182707
Price: $58

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