Endophytes are the microorganisms that occur within the tissues of the plants without causing
any noticeable symptoms and diseases to the host. In general, fungi and bacteria are the most
common microbes exist as endophytes in plants. In recent years, endophytic fungi are known to produce
several bioactive secondary metabolites, mainly used in pharmaceutical, agricultural and industrial
applications. This review describes the isolation of naturally occurring bioactive compounds from
endophytic microorganisms. In the recent past, a wealth of information on the isolation and purification
of bioactive secondary metabolites from various endophytes have been reported. As endophytes
produce these secondary metabolites in lower concentrations, it is required to employ improved isolation and purification
methods of these secondary metabolites for their complete recovery.
Keywords: Bioactive compounds, endophytes, host plants, isolation, purification, secondary metabolites.
Rights & PermissionsPrintExport