Telocytes (TCs) are a newly identified interstitial cell type which are named after and characterized
by specialized thin, long synaptic structures called telopodes (Tps). The existence of TCs has
been reported in lots of tissues and organs. There are numerous on-going studies to explore the biological
functions of TCs, including their involvement in human disease. TCs are generally considered
as supporting cells that help maintain the micro-structure of tissues by forming a three-dimensional interstitial
network via intercellular junctions. In addition, TCs have also been implicated in the regulation
of stem cell activity and the stem cell niche microenvironment, thus contributing to tissue repair
and renewal. In this review, the most recent findings concerning hepatic TCs are described.
Keywords: Telocytes, liver, regeneration, fibrosis.
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