Telocytes in Liver

Author(s): Jingqi Liu, Yan Cao, Yang Song, Qi Huang, Fei Wang, Wenzhuo Yang, Changqing Yang.

Journal Name: Current Stem Cell Research & Therapy

Volume 11 , Issue 5 , 2016

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Abstract:

Telocytes (TCs) are a newly identified interstitial cell type which are named after and characterized by specialized thin, long synaptic structures called telopodes (Tps). The existence of TCs has been reported in lots of tissues and organs. There are numerous on-going studies to explore the biological functions of TCs, including their involvement in human disease. TCs are generally considered as supporting cells that help maintain the micro-structure of tissues by forming a three-dimensional interstitial network via intercellular junctions. In addition, TCs have also been implicated in the regulation of stem cell activity and the stem cell niche microenvironment, thus contributing to tissue repair and renewal. In this review, the most recent findings concerning hepatic TCs are described.

Keywords: Telocytes, liver, regeneration, fibrosis.

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Article Details

VOLUME: 11
ISSUE: 5
Year: 2016
Page: [415 - 419]
Pages: 5
DOI: 10.2174/1574888X10666150630112035
Price: $58

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