Cyclization: A Useful Approach for the Synthesis of Nitrogen Heterocyclic N-Oxides

Author(s): Ning Liu, Yuan-Jie Shu, Bo-Zhou Wang, Xiang-Zhi Li, Fu-Qiang Bi.

Journal Name: Current Organic Chemistry

Volume 19 , Issue 19 , 2015

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Abstract:

Nitrogen heterocyclic N-oxides attract enormous interest in synthetic chemistry, medicinal chemistry, functional materials and energetic materials. Cyclization reaction turns out to be an important and highly rewarding protocol for the construction of N-heterocyclic N-oxides and different types of organonitrogen compound could be utilized as crude materials. In this work a review of recent advancement in the generation of pyrazole, imidazole, triazole, triazine, tetrazine, isoquinoline and other N-heterocyclic N-oxides and their derivatives via cyclization reactions is presented.

Keywords: Nitrogen heterocyclic N-oxides, cyclization, mechanism, synthesis.

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Article Details

VOLUME: 19
ISSUE: 19
Year: 2015
Page: [1896 - 1915]
Pages: 20
DOI: 10.2174/1385272819666150622174626
Price: $58

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