This is the first report on the organocatalytic activity of simple unsubstituted p-tertbutylcalix[
8]arene, C8 towards multi-ring heterocycles. We thereby account an expeditious, ecofriendly,
high throughput procedure of the synthesis of some biologically active cores xanthenes and
acridines along with spiro-derivatives of both with the aid of the organocatalyst C8. The catalyst is
recyclable for at least six cycles without substantial loss of activity.
Keywords: Acridines, eco-friendly solvent, nano-ranged, organocatalyst, p-tert-butylcalixarene,
recyclable, spiro-derivatives, xanthenes.
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