Neurodegenerative diseases are characterized by a progressive deterioration of brain function,
with a consequent significant decline in the quality of life of patients and their families. Due to
the concurrent increase in life expectancy, the incidence of these diseases has been increasing over the
last years and thus there is a growing interest in finding potential risk factors. This review focuses on
the correlation between peripheral inflammatory diseases and neurodegeneration, in particular on the
relationship between gastrointestinal disorders and Parkinson's disease, especially through the so
called gut-brain axis.
Keywords: Gut-brain axis, Inflammatory bowel disease, Microglia, Neurodegeneration, Parkinson’s disease, Peripheral inflammation.
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