Benzyltriphenylphosphonium Chloride: A Efficient Catalyst for One-Pot Synthesis of Dihydropyrimidinones/Thiones under Solvent-Free Conditions

Author(s): Mohammad Alikarami, Ronak Moradi.

Journal Name: Letters in Organic Chemistry

Volume 12 , Issue 8 , 2015

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Graphical Abstract:


An efficient and one-pot method for the preparation of 3,4-dihydropyrimidin-2(1H)- ones/thiones is described. Benzyltriphenylphosphonium chloride (BTPPC) under solvent free conditions catalyzes this multi-component condensation reaction to afford the corresponding dihydropyrimidinones/thiones in good yields.

Keywords: Multi-component condensation, one-pot synthesis, benzyltriphenylphosphonium chloride, 3, 4-dihydropyrimidin-2(1H)-ones/thiones, solvent-free.

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Article Details

Year: 2015
Page: [560 - 565]
Pages: 6
DOI: 10.2174/1570178612666150528212749
Price: $58

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