Diversity oriented, efficient and environmentally benign synthetic protocol has been presented for the
synthesis of spiroquinazolinones. The hybrid drug-like small molecules incorporating medicinally privileged heterocyclic
systems have been synthesized by tandem reaction of 3-aminocrotonnitrile, phenyl hydrazine/ hydrazine
hydrate, isatoic anhydride and isatin using deep eutectic solvent as efficient catalyst and environmentally benign
Keywords: Deep eutectic solvent, HBD (Hydrogen bond donor), Ionic liquid, Tandem reaction, Privileged heterocyclic structure, Spiroquinazolinone.
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