Inflammation is a beneficial response that can remove pathogens, repair injured tissue
and restore homeostasis to damaged tissues and organs. However, increasing evidence indicate
that chronic inflammation plays a pivotal role in tumor development, as well as progression,
metastasis, and resistance to chemotherapy. We will review the current knowledge regarding the
contribution of inflammation to epithelial mesenchymal transition. We will also provide some perspectives on the relationship between
ER-stress signals and metabolism, and the role of these processes in the development of inflammation.