An efficient and mild method for thioacetalization of 2-alkynylbenzaldehydes in the
presence of a catalytic amount of silver triflate has been described. This reaction proceeded efficiently
to generate 2-alkynylbenzaldehydes thioacetals in good to excellent yields at room temperature within
short reaction time (no more than 30 min). This transformation was extremely easy to perform without
the need of using anhydrous solvent and inert atmosphere. Chemoselective thioacetalization of benzaldehyde in the presence
of acetophenone was also demonstrated.
Keywords: 2-Alkynylbenzaldehyde, Silver triflate, Thioacetalization, Thioacetal, Thiol.
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