Critical Review of Malondialdehyde Analysis in Biological Samples

Author(s): Maryam Khoubnasabjafari , Khalil Ansarin , Abolghasem Jouyban .

Journal Name: Current Pharmaceutical Analysis

Volume 12 , Issue 1 , 2016

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Abstract:

Malondialdehyde (MDA) is one of the most common biomarkers of oxidative stress and is used for the diagnosis of many diseases. This work aims to review the reaction used for the derivatization of MDA, the parameters affecting adduct formation, and a number of recently published analytical methods for quantification of MDA in biological samples. A brief discussion of the reliability of MDA as an oxidative stress biomarker is also provided.

Keywords: Oxidative stress, biomarker, malondialdehyde, serum analysis, bioanalysis, review.

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Article Details

VOLUME: 12
ISSUE: 1
Year: 2016
Page: [4 - 17]
Pages: 14
DOI: 10.2174/1573412911666150505185343
Price: $58

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