Psychopharmacological Issues in Geriatrics

Psychopharmacological Issues in Geriatrics

Indexed in: EBSCO.

Demographic changes due to improved life expectancy and access to medical care has increased the number of people aged 65 years and beyond. This raises an important new challenge for healthcare ...
[view complete introduction]

US $

*(Excluding Mailing and Handling)

Antipsychotics in Dementia

Pp. 241-271 (31)

Juan Medrano


Dementia is a common off-label use of antipsychotics. However, there are neither controlled studies, nor theoretical grounds supporting their use, especially in the treatment of behavioral disorder, where antipsychotics behave mainly as the “major tranquillizers” they once were meant to be. On the other hand, antipsychotics pose serious risks to elderly, fragile patients with dementia. As a result, treating dementia with antipsychotics could be a case in point of an irrational use of drugs. The chapter reviews untoward effects linked to antipsychotics when used in dementia and suggests some guidelines to make its use less irrational.


Akathisia, Alzheimer’s disease, Behavioral and psychological symptoms of dementia (BPSD), Behavioral disorder, Cardiac arrhythmia, Cerebrovascular disorder, Clozapine, Confabulation, Delirium, Dementia, Firstgeneration antipsychotics- Haloperidol, Lewy body disease, Misidentification syndrome, Mortality, Off-label, Olanzapine, Psychosis, Quetiapine, Rational use of drugs, Risperidone, Second-generation antipsychotics, Tardive dyskinesia, Vascular dementia, Venous thromboembolism.


Ezkerraldea - Enkarterri Mental Health Community Services, Bizkaia`s Mental Health Network, Portugalete, Bizkaia/Vizcaya, Spain.