Pp. 187-216 (30)
Antidepressants are drugs used for the treatment of depression and many
other psychiatric conditions. Albeit belonging to different chemical families and with a
number of mechanisms of action, all of them enhance neurotransmitters at the synaptic
cleft. They have a range of adverse effects and effectiveness compared with placebo,
according to meta-analysis. However, they have shown to be efficacious in the elderly.
Second-generation antidepressants are safer and better tolerated, but not devoid of side
effects, something not to be forgotten when treating a population in which frailty and
polypharmacy are common.
Antidepressants, Arrhythmia, Bipolar disorder, Bupropion,
Citalopram, Depression, Duloxetine, Early onset depression, Escitalopram,
Hypericum perforatum, Hyponatremia, Late onset depression, Lithium,
Mirtazapine, Monoamine oxidease Inhibitors (MAOIs), Obsessive-compulsive
disorder, Pharmacokinetic interactions, Rapid cycling, Seizures, Selective
serotonin reuptake inhibitors, Serotonin and noradrenalin reuptake inhibitors
(SSRIs), Sertraline, Suicide, Trazodone, Tricyclic antidepressants.
Ezkerraldea - Enkarterri Mental Health Community Services, Bizkaia`s Mental Health Network, Portugalete, Bizkaia/Vizcaya, Spain.