Molecular Targets of Omega-3 Fatty Acids for Cancer Therapy
K. Pandima Devi,
G. L. Russo,
S. F. Nabavi,
S. M. Nabavi.
Nowadays, dietary guidelines acknowledge the therapeutic role of omega-3
polyunsaturated fatty acids, as the most important class of fatty acids, against different
human diseases. During the last two decades, the average level of consumption of
omega-3 polyunsaturated fatty acids has increased from 0.1 to 0.2 g per day. Omega-3 polyunsaturated fatty acids are a
group of long-chain polyunsaturated fatty acids which are identified in different foods such as fatty fish, shellfish, and
vegetable oils. A growing body of epidemiological and experimental evidence supports the anticancer effects of omega-3
polyunsaturated fatty acids, which led to the identification of their molecular targets in several cancer models. The present
review focuses on the basic evidence supporting the potential applications of omega-3 polyunsaturated fatty acids in
Keywords: Anticancer, fish oil, molecular targets, omega-3 polyunsaturated fatty acids.
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