Nanotoxicity: The Toxicity Research Progress of Metal and Metal- Containing Nanoparticles

Author(s): Lingling Ding , Zhidong Liu , Mike Okweesi Aggrey , Chunhua Li , Jing Chen , Ling Tong .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 15 , Issue 7 , 2015

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Abstract:

Along with the exuberant development of nanotechnology, a large number of nanoformulations or non materials are successfully applied in the clinics, biomedicine, cosmetics and industry. Despite some unique advantages of nanoformulations, there exist potentially worrying toxic effects, particularly those related to metal and metal-containing nanoparticles (NPs). Although various researches have been conducted to assess the metallic and metal-containing nanoparticles toxic effects, only little is known about the toxicity expressive types and evaluation, reasons and mechanisms, influencing factors and research methods of metal and metal-containing nanotoxicity. Therefore, it is of importance to acquire a better understanding of metal and metal-containing nanoparticles toxicity for medical application. This review presents a summary on the metal and metal-containing nanoparticles toxicity research progress consulting relevant literature.

Keywords: Influencing factors, metal and metal-containing nanoparticles, reason and mechanism, research methods, toxicity expressive types, toxicity research progress.

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Article Details

VOLUME: 15
ISSUE: 7
Year: 2015
Page: [529 - 542]
Pages: 14
DOI: 10.2174/138955751507150424104334
Price: $58

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