Frontiers in Nanomedicine

Volume: 1

Frontiers in Nanomedicine offers an up-to-date understanding of nanomaterials to readers having clinical or biomolecular research interests. Scientists, both aspiring and experienced, will find, in ...
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Emerging Use of Nanotechnology for the Treatment of Liver Diseases

Pp. 47-83 (37)

Melchiorre Cervello, Lydia Giannitrapani, Maria Rita Emma, Giuseppa Augello, Antonella Cusimano, Daniele Balasus, Antonina Azzolina, Maurizio Soresi and Giuseppe Montalto

Abstract

Liver diseases, including viral hepatitis, resulting from hepatitis B or C virus infection, liver cirrhosis and hepatocellular carcinoma pose great global health challenges due to the limited curative treatment options. The application of nanoparticles has emerged as a rapidly evolving area for safely delivering therapeutic agents (i.e. drugs and nucleic acid) to treat a range of diseases, including those of the liver. In this chapter, we give an overview of various nanotechnology approaches which can be employed when treating liver diseases, focusing in particular on liver infections, fibrosis and cancer.

Keywords:

Drug delivery, HBV, HCC, HCV, liver cirrhosis, liver diseases, liver fibrosis, nanoparticles.

Affiliation:

Institute of Biomedicine and Molecular Immunology "Alberto Monroy", National Research Council (CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy.