In recent years, severe infections caused by the Gram positive pathogen Staphylococcus
aureus have emerged both in community and clinical settings. The increased infection rates are explained
by the versatility and resistance of this pathogen, which produces a wide arsenal of virulence
factors, organize within difficult to eradicate biofilms and displays various resistance genes, leading
current antibiotic therapies ineffective. Nanotechnological progress highlights the impact of magnetic nanoparticles in the
current and future diagnosis and therapy procedures of the infectious diseases. These nanostructures could be used as efficient
carriers for many natural and synthetic antimicrobials, which may be further utilized for the development of soluble
anti-Staphylococcal formulations and improved surfaces and coatings of different uses, optimized to reduce attachment
and biofilm formation.
Keywords: Biofilms, Magnetic nanoparticles, Novel antimicrobials, Resistant pathogens, Staphylococcus aureus, Virulence.
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