Twenty-five years after the emergence of powerful molecular recognition elements known
as aptamers, these synthetic receptors are finding applications in therapeutics, imaging, diagnostics
and biosensors. Comparisons have been drawn between aptamers and antibodies since their earliest
days. This review will highlight how some of the most promising and successful aptamer-based applications
have exploited the advantages aptamers have over their antibody counterparts and will point to
future applications of this enabling technology.
Keywords: Antibodies, Aptamers, Biosensors, Imaging, SELEX, Therapeutics.
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