Generic placeholder image

Current Analytical Chemistry

Editor-in-Chief

ISSN (Print): 1573-4110
ISSN (Online): 1875-6727

A Novel Multi-functional Fluorescent Probe for Cu2+, Fe3+ and Ag+ Based on a Pyrimidine Thiourea Derivative

Author(s): Hassan H. Hammud, Mohammad H. El-Dakdouki, Nada Sonji, Ghassan Sonji and Kamal H. Bouhadir

Volume 11, Issue 4, 2015

Page: [279 - 290] Pages: 12

DOI: 10.2174/1573411011666150324231041

Price: $65

Abstract

A multi-functional “turn-off” fluorescent probe, N-[[(6-Amino-1,2,3,4-tetrahydro-1,3- dimethyl-2,4-dioxo-5-pyrimidinyl)amino]thioxomethyl]- benzamide, was synthesized and characterized. The probe showed high sensitivity and selectivity towards copper(II), iron(III) and silver(I) ions via quenching of its fluorescence. The detection limits were found to be 4.0 – 16.0 ppb for the assayed cations. The thiourea linked uracil fluorescent probe is proved to be sensitive, selective, applicable in real samples and promise for practical applications.

Keywords: 5, 6-diamino-1, 3-dimethyluracil, fluorescent probe, silver, ferric, cupric ion, sensor.


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy