Fibromyalgia (FM), clinical condition characterized by several signs and symptoms such as widespread pain,
trigger point, morning stiffness and extreme tiredness for scarce hours of sleep, is linked to several changes in several brain
neurotransmitters, particularly serotonin and norepinephrine. Consequently, the Neural Vegetative System works more and
so it generates an exaggerated muscular contraction, sweating and constriction of blood vessels. The aim of our study was
to treat a selected group of female patients suffering from FM with duloxetine with physiotherapy. We used two clinical
scales (VAS and FIQ) and an objective evaluation such as myometric. The analysis of the data Myoton used during any
inspection showed a statistically significant reduction in the values of muscle tone in each district analyzed. This finding
was also confirmed by the patients themselves who have experienced a significant welfare and less muscle tension in
different locations, as evidenced by data obtained from the clinical scales used by us. In addition, our patients were
thought to be satisfied with the improvements not only subjective, but also with the objective witnessed myometry,
making them a share of the study and feeling constantly monitored for treatment aimed at a real reduction in muscle
stiffness. In conclusion, our study demonstrates combined treatment duloxetine- physiotherapy effectively reduces a
symptom often disabling and particularly troublesome in patients with FM as the exaggerated muscle contraction.
Keywords: Duloxetine, fibromyalgia, myometry, muscle tension, physiotherapy, vegetative system.
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