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Mini-Reviews in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Synthesis of α-Hydroxyphosphinates and Derivatives: Recent Advances

Author(s): Stamatia Vassiliou

Volume 12, Issue 3, 2015

Page: [237 - 248] Pages: 12

DOI: 10.2174/1570193X12666150320233327

Price: $65

Abstract

α-Hydroxyphosphinates, displaying a wide range of activities from agriculture to medicine as fungicides or metalloenzyme inhibitors, are compounds of high interest. In particular, α- hydroxyalkylphosphinates, bis(α-hydroxyalkyl)phosphinates, optically active form of these compounds as well as their derivatives receive continuously growing synthetic attention. Their synthesis, although impressively old, has never been reviewed. This review covers mainly the data published over the last ten years (2004-2014).

Keywords: Amino acid, metalloenzymes, organophosphorus, phosphinic, phosphorus, α-hydroxyalkyl.

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