Gastrointestinal disorders are frequently accompanied by symptoms exceeding gastrointestinal
tract. This is at least partially connected with the involvement of autonomic nervous system in
pathophysiology of diseases such as inflammatory bowel disease (IBD), irritable bowel syndrome
(IBS) or spectrum of motility disorders. In light of the above, involvement of cardiovascular system in
natural history of gastrointestinal disorders seems to be of interest. On the other hand, available data
regarding the prevalence of cardiac rhythm disturbances in IBD, IBS and motility disorders is limited.
What is more, pharmacotherapy of the mentioned diseases includes drugs with possible arrhythmogenic
potential. In this review we present current experiences and observations concerning gastrointestinal
disorders and cardiac rhythm disturbances.
Keywords: Autonomic nervous system, cardiac arrhtytmia, inflammatory bowel disease, irritable bowel syndrome, proarrhythmic
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