Abstract
Isatin is a heterocyclic moiety which can be used for the synthesis of a large variety of heterocyclic compounds such as quinolines, indoles and as raw material for medicinal important drugs. This review gives an overview of the advances of isatin for the synthesis of various heterocyclic compounds and shows the various biological potentials such as anticonvulsant, sedative, hypnotic, monoamine oxidase inhibitors, antianxiety, antipsychoactives activity etc. Isatin derivatives displayed as potent anticonvulsant potential in a large variety of preclinical anticonvulsant models. Present review article is an attempt to compile the various central nervous system potential of synthesized isatin analogs which will serve as a valuable source of information for the researchers working in this field.
Keywords: Isatin, anticonvulsant, sedative, hypnotic, monoamine oxidase inhibitors.
Central Nervous System Agents in Medicinal Chemistry
Title:A Mini Review on Central Nervous System Potential of Isatin Derivatives
Volume: 15 Issue: 1
Author(s): Priyanka Phogat and Pritam Singh
Affiliation:
Keywords: Isatin, anticonvulsant, sedative, hypnotic, monoamine oxidase inhibitors.
Abstract: Isatin is a heterocyclic moiety which can be used for the synthesis of a large variety of heterocyclic compounds such as quinolines, indoles and as raw material for medicinal important drugs. This review gives an overview of the advances of isatin for the synthesis of various heterocyclic compounds and shows the various biological potentials such as anticonvulsant, sedative, hypnotic, monoamine oxidase inhibitors, antianxiety, antipsychoactives activity etc. Isatin derivatives displayed as potent anticonvulsant potential in a large variety of preclinical anticonvulsant models. Present review article is an attempt to compile the various central nervous system potential of synthesized isatin analogs which will serve as a valuable source of information for the researchers working in this field.
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Cite this article as:
Phogat Priyanka and Singh Pritam, A Mini Review on Central Nervous System Potential of Isatin Derivatives, Central Nervous System Agents in Medicinal Chemistry 2015; 15 (1) . https://dx.doi.org/10.2174/1871524915666150213122246
DOI https://dx.doi.org/10.2174/1871524915666150213122246 |
Print ISSN 1871-5249 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6166 |
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