A convenient diversity oriented synthetic procedure for the construction of various oxo-xanthenes such as 12-
aryl-8,9,10,12-tetrahydrobenzo[a]-xanthene-11-ones, 9-aryl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-diones and 9-
substituted-2,3,4,9-tetrahydro-1H-xanthen-1-ones has been developed by using p-dodecylbenzenesulfonic acid as an efficient
Brønsted acid catalyst under solvent-free microwave conditions. The present methodology is found to be operationally
simple and demonstrates many advantages including shorter reaction times, easy purification steps and good to excellent
yields of the target products.
Keywords: 9-Aryl-3, 4, 5, 6, 7, 9-hexahydro-1H-xanthene-1, 8(2H)-diones, 9-substituted-2, 3, 4, 9-tetrahydro-1H-xanthen-1-ones,
12-aryl-8, 9, 10, 12-tetrahydrobenzo[a]-xanthene-11-ones, Brønsted acid surfactant combined catalyst, eco-friendly protocol,
microwave-assisted synthesis, mild process, multi-component reactions, one-pot methodology, oxo-xanthenes, p-dodecylbenzenesulfonic
acid, single crystal XRD data, solvent-free conditions.
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