Carbon dioxide (CO2) has been regarded as one of the most important greenhouse gases.
Microalgae are considered as a potential solution for the decrease of atmospheric CO2 levels. The design
of photobioreactors capable of capturing CO2 for bioconversion bioproducts is the main issue for
techno-economic success in the field of phototrophic biotechnology. There are two kinds of large
scale photobioreactors: open and closed system. The open systems are raceway ponds and closed systems are the flat
plate, vertical tubular and horizontal tubular. These photobioreactors have their own advantages and disadvantages. Improvements
in the design and configuration of photobioreactors are widely evaluated, with a focus on the utilization of
physical parameter suitable for scaling. However, some considerations must be taken into account such as the
height/diameter (H/D) ratio, an appropriate value, which maintains control from the structural and physicochemical point
of view, helping to provide sufficient volume of microalgae culture, efficient transfer of mass, a reaction volume where
light input to the system is adequate, good rate of culture mixture and better utilization of land space. This review seeks to
show some photobioreactor designs, some patents and their scale-up to be implemented in the CO2 sequestration and biomass
Keywords: Biomass, bioproducts, carbon dioxide, microalgae, photobioreactor, scale-up.
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