Transition-Metal-Catalyzed Oxidative and Decarboxylative Acylations through sp2 C-H Bond Activation

Author(s): Satyasheel Sharma, Neeraj Kumar Mishra, Youngmi Shin, In Su Kim.

Journal Name: Current Organic Chemistry

Volume 20 , Issue 5 , 2016

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Abstract:

Transition-metal-catalyzed oxidative and decarboxylative acylations of sp2 C-H bonds bearing conventional directing groups with various acyl equivalents, such as aldehydes, alcohols, alkylbezenes, -keto acids, etc. are described. These protocols present an effective and promising route to obtain aryl ketones, which are found to be important precursors for the formation of bioactive molecules and functional materials. Thus, oxidative and decarboxylative C-H acylations potentially provide a catalytic alternative to overcome the limitations of classical Friedel-Crafts acylation. This review is intended to give an overview on recent advances on catalytic acylation reactions through C-H bond activation.

Keywords: Acylation, catalytic, decarboxylative, oxidative, transition metal.

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Article Details

VOLUME: 20
ISSUE: 5
Year: 2016
Page: [471 - 511]
Pages: 41
DOI: 10.2174/1385272819666150122234834
Price: $58

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