Abstract
RNAi based therapeutics hold s great promises to be an efficient strategy of the anti-gene realm in context of its therapeutic applications; however, despite significant potentials, its full efficacy cannot be realized in real sense owing to various confronts that plague its advancement. Efforts need to be driven for the development of specific and efficacious strategies to subdue some of their crucial constraints towards successes in clinics. This article will present the major impediments that encumber successful translation of siRNA concept into reality and the ongoing research endeavours to get through those stumbling blocks along with their inadequacies.
Keywords: Anti-gene, efficacious, RNAi, safe, therapeutic.
Current Gene Therapy
Title:SiRNA Nanotherapeutics _The Panacea of Diseases?
Volume: 15 Issue: 2
Author(s): Khan Farheen Badrealam, Swaleha Zubair and Mohammad Owais
Affiliation:
Keywords: Anti-gene, efficacious, RNAi, safe, therapeutic.
Abstract: RNAi based therapeutics hold s great promises to be an efficient strategy of the anti-gene realm in context of its therapeutic applications; however, despite significant potentials, its full efficacy cannot be realized in real sense owing to various confronts that plague its advancement. Efforts need to be driven for the development of specific and efficacious strategies to subdue some of their crucial constraints towards successes in clinics. This article will present the major impediments that encumber successful translation of siRNA concept into reality and the ongoing research endeavours to get through those stumbling blocks along with their inadequacies.
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Cite this article as:
Badrealam Farheen Khan, Zubair Swaleha and Owais Mohammad, SiRNA Nanotherapeutics _The Panacea of Diseases?, Current Gene Therapy 2015; 15 (2) . https://dx.doi.org/10.2174/1566523215666150122130047
DOI https://dx.doi.org/10.2174/1566523215666150122130047 |
Print ISSN 1566-5232 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5631 |
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