Current Gene Therapy

Ignacio Anegon
Director INSERM UMR 1064-Center for Research in Transplantation and Immunology
CHU de Nantes. 30, boulevard
Nantes
France

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SiRNA Nanotherapeutics _The Panacea of Diseases?

Author(s): Khan Farheen Badrealam, Swaleha Zubair, Mohammad Owais.

Abstract:

RNAi based therapeutics hold s great promises to be an efficient strategy of the anti-gene realm in context of its therapeutic applications; however, despite significant potentials, its full efficacy cannot be realized in real sense owing to various confronts that plague its advancement. Efforts need to be driven for the development of specific and efficacious strategies to subdue some of their crucial constraints towards successes in clinics. This article will present the major impediments that encumber successful translation of siRNA concept into reality and the ongoing research endeavours to get through those stumbling blocks along with their inadequacies.

Keywords: Anti-gene, efficacious, RNAi, safe, therapeutic.

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Article Details

VOLUME: 15
ISSUE: 2
Year: 2015
Page: [201 - 214]
Pages: 14
DOI: 10.2174/1566523215666150122130047
Price: $58