A green, efficient and operationally simple method for three-component synthesis of 1,2,3-
trisubstituted pyrrole derivatives via an iodine-catalyzed tandem reaction has been developed, and a
series of 1,2,3-trisubstituted pyrrole derivatives were synthesized from simple starting materials under
neutral conditions, with good to excellent yields in short time. This method showcased the potential of
great value as a mild, rapid, and general procedure for the synthesis of 1,2,3-trisubstituted pyrroles.