We describe here a simple and rapid protocol for the synthesis of (arylselanyl)phenyl-1H-
1,2,3-triazoles by copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions using Microwave
Irradiation. The products were obtained under mild conditions in excellent yields in a short reaction
time by reacting azidophenyl arylselenides with a range of terminal alkynes using catalytic amount of
Cu(OAc)2.H2O/sodium ascorbate. This Click Chemistry protocol is an efficient method to synthesize
new selenium compounds with potential application in biological studies and materials sciences.
Keywords: Alkynes, azides, catalysis, 1, 3-dipolar, click chemistry, copper, cycloaddition, green chemistry, heterocycles, microwave,
1, 2, 3-triazoles, nitrogen compounds, selanyltriazoles, selenium compounds.
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