Individual microRNAs and/or microRNA signatures were associated with Alzheimer’s
disease (AD). We report here the recent advances brought to the identification of microRNA
changes in AD brain and their biological function in the molecular pathways associated with the
disease. This field represents a fertile route to understand the pathogenic mechanisms underlying
Alzheimer’s disease. In addition we review recent studies aimed to discover promising biomarkers
for AD diagnosis by microRNA expression profiles of biofluids from AD patients.
Keywords: Alzheimer’s disease, APP, microRNAs, tau.
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