A Rapid, Efficient Method for Deprotection of Oximes to Carbonyl Compounds with NaClO2 in Water

Author(s): Yuan-Yuan Yao, Xian-Liang Zhao.

Journal Name: Letters in Organic Chemistry

Volume 12 , Issue 1 , 2015

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Abstract:

A rapid, efficient method for deprotection of oximes to carbonyl compounds is demonstrated by using sodium chlorite (NaClO2) in water. The protocol has been found to be applicable to a wide range of aldoximes and ketoximes with good to excellent yields of the corresponding carbonyl compounds.

Keywords: Sodium chlorite, oximes, carbonyl compounds, aqueous conditions.

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Article Details

VOLUME: 12
ISSUE: 1
Year: 2015
Page: [73 - 76]
Pages: 4
DOI: 10.2174/157017861201150112125024

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