Kabachnik-Fields Reaction Under Green Conditions – A Critical Overview

Author(s): Pawel Kafarski, Michal Gorny vel Gorniak, Iga Andrasiak.

Journal Name: Current Green Chemistry

Volume 2 , Issue 3 , 2015

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Graphical Abstract:


Three-component one-pot Kabachnik-Fields condensation of carbonyl compounds with amines and phosphites is perhaps the most exploited reaction for the preparation of structurally diverse -aminophosphonates. Most of the described protocols might be considered to some extent as green ones with solvent-free and microwave-assisted ones being the most effective.

Keywords: Phospha-mannich reaction, hydrophosphonylation, green chemistry, catalysis.

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Article Details

Year: 2015
Page: [218 - 222]
Pages: 5
DOI: 10.2174/2213346102666150109203606
Price: $58

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