Nanoparticles in the Treatment of Mental Disorders: A New Tool in the Psychiatric Medication

Author(s): Eduardo Sobarzo-Sánchez, Seyed Mohammad Nabavi, Eugenio Uriarte, Lourdes Santana.

Journal Name: Current Topics in Medicinal Chemistry

Volume 15 , Issue 4 , 2015

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Abstract:

The use of the nanotechnology in the development of new drugs has had in the last years a very widespread presence in the pharmaceutical industry. Diverse diseases that are treated by means of conventional administration systems as capsules, covered tablets or injectable not always have the therapeutic effect expected due to its bioavailability, solubility in aqueous medium and the stability of the excipients that they accompany to the drug. It is for this reason that the formation of nanoparticles either from organic sources as natural polymers like chitosan or synthetic like poly-ε-caprolactone (PCL) affording the inclusion of diverse liposoluble active compounds, they have given excellent results in the incipient treatment of behavior disorders that are necessary drugs that should remain close of active sites at the time. Thus, this review shows the formation of nanoparticles for a direct application of the psychiatric medication, may be considered as a new pharmacological tool by its low cytotoxicity and high efficiency.

Keywords: Mental disorders, Nanoparticles, Nanotechnology, Neurodegenerative diseases.

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Article Details

VOLUME: 15
ISSUE: 4
Year: 2015
Page: [282 - 286]
Pages: 5
DOI: 10.2174/1568026615666150108124533
Price: $58

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