Title:New Naphthyl Esters from the Bark of Ficus religiosa Linn
VOLUME: 4 ISSUE: 4
Author(s):Abuzer Ali, Mohammad Jameel and Mohammed Ali
Affiliation:Phytochemistry Research Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi-110062, India.
Keywords:Ficus religiosa, lanostanoic acid linoleinate, Moraceae, naphthadiolyl linoleinate, naphthyl ester, β-Sitosteryl oleate.
Abstract:Ficus religiosa Linn. (Moraceae) is cultivated in south-eastern Asia as a holy tree. Its bark is
used to treat anxiety, burns, diarrhoea, dysentery, gastrohelcosis, glandular swellings of the neck,
gonorrhoea, hiccup, piles, skin diseases, scabies, urinogenital disorders, vomiting and to improve the
complexion. Phytochemical investigation of the methanolic extract of F. religiosa bark led to the isolation
of two new naphthyl esters characterized as naphthyl-1ʹ,3ʹ-diol-1ʹ-(3β-lanost-5,24-dienyl)-3ʹ-n-octadec-
9ʹʹ,12ʹʹ,15ʹʹ-trienoate (1) and naphthyl-1ʹ,3ʹ-diol-1ʹ-(3β-lanostan-19-oic acid-yl)-3ʹ- n-octadec-9ʹʹ,12ʹʹ-dienoate (3) and a
new triterpenic ester lanostan-19-oic acid-3β-olyl-n-octadec-9ʹ,12ʹ,15ʹ-trienoate (2) along with the known steroids β-sitosteryl
oleate (4) and β -sitosterol glucoside (5). The structures of all these isolated phytoconstituents were established on the
basis of spectral data analysis and chemical reactions.
