The Natural Products Journal

Bin Wu
Zhejiang University


Composition and Antimicrobial Activity of the Essential Oils from the Leaves and Flowers of Lippia stachyoides var. martiana (Verbenaceae)±

Author(s): Rafael F. Silva, Claudia M. Rezende, Hellen C. D. Santana, Roberto F. Vieira, Rosa B. N. Alves, Daniela S. Alviano, Celuta S. Alviano, Marcelly C. S. Santos, Humberto R. Bizzo.

Graphical Abstract:


The chemical composition of the essential oil from the leaves and flowers of Lippia stachyoides var. martiana (Verbenaceae) from the Brazilian Cerrado was analyzed by GC/FID and GC/MS. Fifty-seven and forty-one essential oil constituents were identified in the flowers and leaves, respectively, being thirty-eight substances found in both oils. Flowers and leaves essential oils were rich in (E)-nerolidol (15.6 and 16.4%), δ-cadinene (15.8 and 18.5%), spathulenol (8.1 and 16.4%), caryophyllene oxide (6.6 and 7.8%) and cubebol (8.5 and 7.4%), respectively. Both essential oils also showed promising results against yeast-like fungi and bacteria. Good antifungal activity was observed for Cryptococcus neoformans, with MIC’s of 156 μg/ml and 78 μg/ml for flowers and leaves oils, respectively.

Keywords: Brazilian Cerrado, essential oil, gas chromatography, Lippia stachyoides var. martiana, Verbenaceae.

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Article Details

Year: 2014
Page: [241 - 247]
Pages: 7
DOI: 10.2174/2210315505666141226195643
Price: $58