Title:Antitumor Metabolites of Fungi
VOLUME: 10 ISSUE: 4
Author(s):Rosario Nicoletti and Antonio Fiorentino
Affiliation:Dipartimento di Agraria, Universita di Napoli ‘Federico II’, Via Universita 100, 80055, Portici, Italy.
Keywords:Antitumor drugs, biological activity, fungi, natural products, secondary metabolites.
Abstract:The exploitation of the antitumor properties of fungal secondary metabolites is one of the fundamental
objectives pursued by a multiplicity of research groups and laboratories working on the characterization
of natural products worldwide. The availability of a synthetic framework on such a vast interdisciplinary
topic can enhance the current knowledge by supporting novel findings, and stimulating further insights. This paper offers
an overview of the state-of-the-art concerning this category of compounds and their occurrence, selection, structural diversity
and mechanisms of action on tumor cells.
