Current Bioactive Compounds

Adriano Mollica
Department of Pharmacy, University ”G. d' Annunzio” of Chieti-Pescara
Via dei Vestini 31
Chieti, 66100
Italy

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Antitumor Metabolites of Fungi

Author(s): Rosario Nicoletti, Antonio Fiorentino.

Abstract:

The exploitation of the antitumor properties of fungal secondary metabolites is one of the fundamental objectives pursued by a multiplicity of research groups and laboratories working on the characterization of natural products worldwide. The availability of a synthetic framework on such a vast interdisciplinary topic can enhance the current knowledge by supporting novel findings, and stimulating further insights. This paper offers an overview of the state-of-the-art concerning this category of compounds and their occurrence, selection, structural diversity and mechanisms of action on tumor cells.

Keywords: Antitumor drugs, biological activity, fungi, natural products, secondary metabolites.

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Article Details

VOLUME: 10
ISSUE: 4
Year: 2014
Page: [207 - 244]
Pages: 38
DOI: 10.2174/1573407211666141224204809
Price: $58