A Rapid Tandem Knoevenagel/Michael Reaction Using Mohr’s Salt as a Highly Efficient Catalyst: Green Synthesis of Bis(pyrazolyl)methanes

Author(s): Khalil Eskandari , Bahador Karami , Saeed Khodabakhshi , Mahnaz Farahi .

Journal Name: Letters in Organic Chemistry

Volume 12 , Issue 1 , 2015

Become EABM
Become Reviewer

Graphical Abstract:


Abstract:

A convenient access to some new and known bis(pyrazolyl)methanes synthesis has been successfully achieved via an alternative Knoevenagel/Michael reaction of aromatic aldehydes and pyrazole-5-one in the presence of Mohr’s salt as a green catalyst. This novel procedure has some advantages such as high efficiency, simplicity, high rate and environmental safety.

Keywords: Green synthesis, Knoevenagel condensation, Michael addition, aqueous media, bis(pyrazolyl)methane, Mohr’s salt.

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 12
ISSUE: 1
Year: 2015
Page: [38 - 43]
Pages: 6
DOI: 10.2174/1570178612666141204224826

Article Metrics

PDF: 32
HTML: 2