Abstract
Novel oral anticoagulants (NOACs) have been developed as alternatives for vitamin K antagonists (VKAs) for the prevention of thromboembolic events in patients with a variety of medical conditions. In this review, we summarize the current data on NOACs safety and efficacy compared to VKAs and in specific patients’ groups including heart valve replacement, venous thromboembolism, advanced renal failure and the elderly.
Keywords: Efficacy, novel oral anticoagulants, safety, vitamin K antagonists.
Cardiovascular & Hematological Agents in Medicinal Chemistry
Title:Safety and Efficacy of Novel Oral Anticoagulants: A Comparison to Vitamin K Antagonists
Volume: 12 Issue: 1
Author(s): Antonios Katsianis, Emmanouil Petrou, Anna Kostopoulou and George Theodorakis
Affiliation:
Keywords: Efficacy, novel oral anticoagulants, safety, vitamin K antagonists.
Abstract: Novel oral anticoagulants (NOACs) have been developed as alternatives for vitamin K antagonists (VKAs) for the prevention of thromboembolic events in patients with a variety of medical conditions. In this review, we summarize the current data on NOACs safety and efficacy compared to VKAs and in specific patients’ groups including heart valve replacement, venous thromboembolism, advanced renal failure and the elderly.
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Cite this article as:
Katsianis Antonios, Petrou Emmanouil, Kostopoulou Anna and Theodorakis George, Safety and Efficacy of Novel Oral Anticoagulants: A Comparison to Vitamin K Antagonists, Cardiovascular & Hematological Agents in Medicinal Chemistry 2014; 12 (1) . https://dx.doi.org/10.2174/187152571201141201092129
DOI https://dx.doi.org/10.2174/187152571201141201092129 |
Print ISSN 1871-5257 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6182 |
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